Fig. 2.

Western blot of Lrp5, Lrp6 and β-catenin in the cerebellum of CKO mice. (a, b) The cerebellar Lrp5 and Lrp6 protein levels in P17 WT, Lrp5 CKO, Lrp6 CKO, and Lrp5/6 dCKO mice. *p < 0.05, **p < 0.01,*** p < 0.001, vs WT control. (c, d) β-Catenin levels in the cerebellar cytoplasm (c) and in the nucleus (d) are reduced in Lrp5/6 dCKO mice. * p < 0.05, ** p < 0.01, vs WT control. Molecular weight is indicated