Fig. 3.

SERV-K1 Env-specific CD8+ T cell response. a ICS flow plots showing TNF-α and IFN-γ cytokine induction in SERV-K1 Env PA8-responding T cells. b Flow plots display memory subset staining of either bulk CD8+ T cells (left) or SERV-K1 Env PA8-responding CD8+ T cells (right, gated by TNF-α/IFN-γ induction shown in part a). Memory subsets are labeled as follows: N naïve, CM central memory, EM effector memory. Note SERV-K1 Env PA8-specific T cells are uniformly effector memory in phenotype