Table 2.

Association of Cry1 and Cry2 mRNA levels with clinical and pathological features of colorectal cancer patients

			Cry1				Cry2
		n = 50	Median	Q1	Q3	P value	Median	Q1	Q3	P value
Age	<62	16	1.067	0.727	1.315	0.018	0.661	0.318	0.920	0.408
	62-74	19	0.552	0.291	1.078		0.423	0.248	0.770
	>74	15	0.715	0.329	0.943		0.434	0.211	0.742
Gender	Male	34	0.879	0.427	1.398	0.003	0.432	0.236	0.801	0.677
	Female	16	0.686	0.442	0.819		0.551	0.297	0.673
Tumor Location	Proximal colona	17	0.722	0.323	1.078	0.008	0.434	0.254	0.742	0.007
	Transverse colon	6	0.546	0.389	0.649		0.232	0.127	0.309
	Distal colonb	27	0.935	0.560	1.398		0.644	0.280	0.898
Grading	G1/G2	45	0.726	0.427	1.174	0.778	0.477	0.248	0.801	0.925
	G3/G4	5	0.841	0.556	1.270		0.552	0.309	0.675
Modified Dukes Staging System	A	4	0.612	0.419	0.912	0.929	0.326	0.203	0.831	0.397
	B	20	0.770	0.562	1.006		0.429	0.202	0.734
	C	24	0.713	0.375	1.354		0.572	0.275	0.891
	D	2	1.145	0.389	1.901		1.566	0.309	2.823
Histologic Type	Non mucinous adenocarcinoma	45	0.318	0.291	0.552	0.311	0.592	0.270	0.607	0.083
	Mucinous adenocarcinoma	5	0.798	0.509	1.236		0.477	0.254	0.770
MSI frequency	missing	12	-	-	-	0.659	-	-	-	0.555
	High	9	0,560	0,389	1,174		0,550	0,350	0,717
	Low	10	0,770	0,583	1,110		0,403	0,248	0,675
	Stable	19	0,628	0,318	1,078		0,592	0,270	1,043
Tumor extent	2	4	0.612	0.419	0.912	0.582	0.326	0.203	0.831	0.625
	3	43	0.798	0.495	1.270		0.550	0.267	0.801
	4	3	0.389	0.208	1.310		0.309	0.127	0.717
Lymph node involvement	N0	24	0.727	0.502	1.006	0.205	0.438	0.230	0.785	0.482
	N1	14	0.569	0.318	1.270		0.419	0.269	0.715
	N2	12	1.059	0.556	2.020		0.571	0.329	1.135
TNM Stage	I-II	27	0.628	0.323	1.398	0.899	0.552	0.270	1.039	0.247
	III-IV	23	0.727	0.509	1.078		0.434	0.211	0.770
Vascular Invasion	Not	27	0.727	0.509	1.110	0.620	0.552	0.267	0.801	0.621
	Yes	23	0.726	0.389	1.580		0.350	0.248	0.717

^aCaecum and ascending colon ^bDescending colon, sigmoid colon and rectum