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. 2015 Nov 18;30(2):971–982. doi: 10.1096/fj.15-278309

Figure 5.

Figure 5.

GR regulates male-specific inflammatory programs during LPS challenge. A) Nanostring analysis of male GRflox/flox and LGRKO treated with either vehicle or LPS (5 mg/kg) for 4 h showing significantly regulated genes between various comparisons. B) Venn diagram of male GRflox/flox and LGRKO treated with vehicle or LPS. C) Male-specific glucocorticoid target genes regulated in GRflox/flox but not LGRKO in response to LPS challenge. D) Male-specific genes that become induced in response to LPS treatment in male LGRKO mice (n = 3 animals). n.s., not significant. *P < 0.05, **P < 0.01.