Skip to main content
. 2015 Nov 2;30(2):874–883. doi: 10.1096/fj.15-274845

Figure 3.

Figure 3.

BALF adenosine levels and diminished arterial oxygen saturation after DP treatment. A) Wild-type C57BL/6 female mice (n = 5) were exposed to BLM (2.5 U/kg) by oropharyngeal aspiration. DP (5 mg/kg) and its vehicle control were administered by intraperitoneal injection 2 times per day after 14 d of BLM exposure. Mice were killed at d 21. B) BALF adenosine levels examined by HPLC. C) Arterial oxygen saturation in mice. D) Wild-type C57BL/6 male mice (n = 5) were administered BLM (0.035 U/g) by intraperitoneal injection 2 times per week. DP (5 mg/kg), and its vehicle control was administered by intraperitoneal injection 2 times per day after 24 d of BLM exposure. Mice were killed at d 33. E) Adenosine levels in BALF. F) Arterial oxygen saturation in mice. All data are presented as means ± sem. *P < 0.05, **P < 0.01 for difference between PBS and BLM + vehicle groups; #P < 0.05, ##P < 0.01 for difference between BLM + vehicle and BLM + DP groups.