Table 3. Observable odds ratio (OR)a, by sensitivity of birth certificate to identify prenatal smoking, the proportion of non-diseased who smoke, and true OR.
Proportion non-diseased | True disease-smoking odds ratio | |||||
---|---|---|---|---|---|---|
Sensitivity | who smoke | 1.2 | 1.5 | 2.0 | 3.0 | 5.0 |
|
|
|
||||
85% | 0.10 | 1.18 | 1.44 | 1.87 | 2.72 | 4.33 |
0.20 | 1.18 | 1.45 | 1.89 | 2.71 | 4.21 | |
0.30 | 1.18 | 1.44 | 1.86 | 2.63 | 3.93 | |
79% | 0.10 | 1.17 | 1.43 | 1.86 | 2.67 | 4.20 |
0.20 | 1.18 | 1.44 | 1.86 | 2.64 | 4.00 | |
0.30 | 1.18 | 1.43 | 1.82 | 2.52 | 3.66 | |
73% | 0.10 | 1.17 | 1.42 | 1.84 | 2.63 | 4.08 |
0.20 | 1.17 | 1.43 | 1.83 | 2.57 | 3.82 | |
0.30 | 1.17 | 1.41 | 1.78 | 2.43 | 3.44 |
According to the attenuation equation [30]. Assumes non-differential exposure measurement error (sensitivity equal in diseased and non-diseased, specificity = 99% in both diseased and non-diseased), and no error in outcome ascertainment.