Table 3.
Expression of Toll–like receptors (TLR) in human and murine dendritic cell (DC) subsets
| TLR1 | TLR2 | TLR3 | TLR4 | TLR5 | TLR6 | TLR7 | TLR8 | TLR9 | TLR10 | References | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | |||||||||||
| Myeloid DCs (CD11c+) | + | + | + | + | + | + | + | +/− | − | + | 1 |
| CD11c+/CD141+ DC | + | ++ | +++ | − | − | + | − | +/− | − | + | 39 |
| Monocyte‐derived DCs | + | + | + | + | + | +/− | +/− | + | − | + | 1,40 |
| Plasmacytoid DCs (CD11c− BDCA2+ BDCA4+) | +/− | − | − | − | − | − | + | − | + | + | 42 |
| Mouse | |||||||||||
| Conventional DCs (CD11chigh B220−) | |||||||||||
| CD4+ | + | + | − | + | + | + | + | − | + | − | 1 |
| CD4−CD8a− | + | + | +/− | + | + | + | +/− | − | + | − | 1 |
| CD8α+ | + | + | + | + | − | + | − | − | + | − | 1 |
| Plasmacytoid DCs (CD11clow B220+ PDCA‐1+) | + | + | − | + | +/− | + | + | − | + | − | 1 |