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. 2015 Nov 6;106(12):1730–1737. doi: 10.1111/cas.12832

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© 2015 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Dot plot of creatinine‐corrected urine laminin‐γ2 (Ln‐γ2/crn) in patients with urologic diseases. Dot plots of Ln‐γ2/crn in 39 non‐muscle invasive urothelial cancer (NMIUC) patients and 61 patients with other urologic diseases. The mean urine concentration of Ln‐γ2/crn in NMIUC patients was significantly higher than in patients with benign urologic disease (2.07 ± 2.86 and 0.67 ± 0.58 μg/g∙crn, respectively; P = 0.004). Using a cut‐off value of 0.5 μg/g∙crn, the sensitivity and specificity for detecting NMIUC were 97.4 and 45.9, respectively.