Table 1.

List of GO terms significantly enriched in group (a) A gene and (b) B gene

GO acession	GO term	P‐value
(a)
GO:0032963	Collagen metabolic process	2.3 × 10−5
GO:0044259	Multicellular organismal macromolecule	2.5 × 10−5
	metabolic process
GO:0030574	Collagen catabolic process	2.5 × 10−5
GO:0044236	Multicellular organismal metabolic process	2.5 × 10−5
GO:0005615	Extracellular space	2.5 × 10−5
GO:0044243	Multicellular organismal catabolic process	3.5 × 10−5
GO:0031012	Extracellular matrix	8.2 × 10−4
GO:0030198	Extracellular matrix organization	8.2 × 10−4
GO:0043062	Extracellular structure organization	8.2 × 10−4
GO:0005578	Proteinaceous extracellular matri	8.3 × 10−4
GO:0022617	Extracellular matrix disassembly	8.6 × 10−4
GO:0005576	Extracellular region	0.0021
GO:0006955	Immune response	0.0021
GO:0002376	Immune system process	0.0042
GO:0030199	Collagen fibril organization	0.029
GO:0006952	Defense response	0.035
(b)
GO:0005576	Extracellular region	4.9 × 10−8
GO:0060429	Epithelium development	1.7 × 10−5
GO:0044421	Extracellular region part	5.1 × 10−5
GO:0009888	Tissue development	6.7 × 10−5
GO:0048856	Anatomical structure development	3.2 × 10−4
GO:0098590	Plasma membrane region	3.2 × 10−4
GO:0048731	System development	5.3 × 10−4
GO:0005615	Extracellular space	0.0018
GO:0009653	Anatomical structure morphogenesis	0.0019
GO:0030855	Epithelial cell differentiation	0.005
GO:0048468	Cell development	0.0052
GO:0016323	Basolateral plasma membrane	0.0057
GO:0030879	Mammary gland development	0.0057
GO:0007399	Nervous system development	0.0057
GO:0071466	Cellular response to xenobiotic stimulus	0.0057
GO:0009410	Response to xenobiotic stimulus	0.0062
GO:0044767	Single‐organism developmental process	0.0062
GO:0048762	Mesenchymal cell differentiation	0.0062
GO:0014033	Neural crest cell differentiation	0.0072
GO:0032502	Developmental process	0.0072
GO:0048732	Gland development	0.0072
GO:0016324	Apical plasma membrane	0.0081
GO:0014031	Mesenchymal cell development	0.0084
GO:0007275	Multicellular organismal development	0.010
GO:0022612	Gland morphogenesis	0.012
GO:0000902	Cell morphogenesis	0.012
GO:0006805	Xenobiotic metabolic process	0.012
GO:0014032	Neural crest cell development	0.012
GO:0045177	Apical part of cell	0.018
GO:0021675	Nerve development	0.018
GO:0048513	Organ development	0.025
GO:0060444	Branching involved in mammary gland duct morphogenesis	0.026
GO:0001763	Morphogenesis of a branching structure	0.045
GO:0009887	Organ morphogenesis	0.045
GO:0043230	Extracellular organelle	0.045
GO:0060485	Mesenchyme development	0.045
GO:0065010	Extracellular membrane‐bounded organelle	0.045
GO:0070062	Extracellular vesicular exosome	0.045
GO:1903561	Extracellular vesicle	0.045
GO:0002009	Morphogenesis of an epithelium	0.048

(a) Bold indicates GO term including “extracellular” and “collagen.”

(b) Bold indicates GO term related to “morphogenesis” and “development” and “differentiation.”