Table 1.

Development of colorectal aberrant crypt foci (ACF) in KK‐A ^y mice treated with azoxymethane and apocynin

Apocynin, mg/L	No. of mice with ACF	No. of ACF/colorectum					Mean no. of AC/focus
		Proximal	Middle	Distal	Rectum	Total
0	12/12	1.1 ± 1.5	16.9 ± 4.8	38.0 ± 10.0	14.5 ± 8.3	70.5 ± 17.2	1.3 ± 0.1
250	12/12	0.3 ± 0.7	7.8 ± 5.9**	28.0 ± 10.9*	12.1 ± 6.3	48.3 ± 20.6**	1.2 ± 0.1
500	12/12	0.2 ± 0.6	10.8 ± 9.8	32.6 ± 12.8	12.1 ± 4.7	55.8 ± 22.3	1.3 ± 0.1

*P < 0.05, **P < 0.01 versus 0 mg/L. Data are expressed as mean ± SD. AC, aberrant crypt.