Table 5.
Univariate and multivariate analyses of the association between overall survival and prognostic factors in 180 patients with non‐small‐cell lung cancer
| Variable | HR (95%CI) | P‐value |
|---|---|---|
| Univariate | ||
| Age | 1.01 (0.97–1.04) | 0.017* |
| Gender (male vs female) | 2.51 (1.32–5.27) | 0.004* |
| Smoking status (Brinkman index ≥400) | 1.71 (0.99–3.08) | 0.052 |
| Pathologic stage (I vs II–IV) | 2.27 (1.72–3.00) | <0.001* |
| T factor (T1/T2/T3/T4) | 2.65 (1.98–3.53) | <0.001* |
| N factor (N0/N1/N2) | 2.01 (1.46–2.75) | <0.001* |
| M factor (M0/M1) | 3.68 (1.11–9.01) | 0.035* |
| Vessel invasion (positive vs negative) | 2.49 (1.45–4.38) | <0.001* |
| Lymphatic invasion (positive vs negative) | 4.90 (2.63–10.0) | <0.001* |
| Pleural invasion (positive vs negative) | 3.91 (2.30–6.80) | <0.001* |
| Type of surgery (lobar vs sublobar) | 2.44 (1.07–7.03) | 0.031* |
| Psf3 (positive vs negative) | 2.13 (1.24–3.79) | 0.006* |
| Multivariate | ||
| Age | 1.04 (1.01–1.08) | 0.003* |
| Gender (male vs female) | 2.30 (1.17–4.99) | 0.014* |
| Pathologic stage (I vs II–IV) | 1.02 (0.46–2.19) | 0.951 |
| T factor (T1/T2/T3/T4) | 2.58 (1.54–4.41) | <0.001* |
| N factor (N0/N1/N2) | 1.57 (0.82–3.07) | 0.174 |
| M factor (M0/M1) | 1.14 (0.24–6.33) | 0.871 |
| Vessel invasion (positive vs negative) | 1.19 (0.43–1.65) | 0.604 |
| Lymphatic invasion (positive vs negative) | 2.52 (1.15–5.91) | 0.021* |
| Pleural invasion (positive vs negative) | 1.36 (0.69–2.72) | 0.369 |
| Type of surgery (lobar vs sublobar) | 1.53 (0.47–4.35) | 0.456 |
| Psf3 (positive vs negative) | 1.76 (1.01–3.22) | 0.049* |
CI, confidence interval; HR, hazard ratio. *Statistically significant.