TABLE 6.
Admission Cytokine Levels for Men and Women for Both Trauma and Nontrauma Populations
| Variable | Trauma
|
Nontrauma
|
||||
|---|---|---|---|---|---|---|
| Men (n = 1,024) | Women (n = 383) | p | Men (n = 471) | Women (n = 413) | p | |
| IL-1 | 2.7 (2.7–5.6) | 2.7 (2.7–5.3) | 0.48 | 2.7 (2.7–4.6) | 2.7 (2.7–2.8) | 0.27 |
|
| ||||||
| IL-2 | 3.7 (2.7–14.9) | 2.7 (2.7–9.8) | 0.0041 | 3.3 (2.7–13.3) | 2.7 (2.7–10.9) | 0.37 |
|
| ||||||
| IL-4 | 38.2 (6.7–214) | 31.2 (5.9–214) | 0.50 | 45.1 (4.9–223) | 29.2 (6.1–160) | 0.28 |
|
| ||||||
| IL-6 | 149 (54.7–374) | 164 (68.4–353) | 0.61 | 153 (47.7–487) | 134 (41.3–394) | 0.38 |
|
| ||||||
| IL-8 | 32.8 (13.5–67.3) | 29.9 (12.5–64.4) | 0.61 | 54.1 (20.9–120) | 41.9 (13.1–99.0) | 0.036 |
|
| ||||||
| IL-10 | 53.0 (21.8–129) | 51.4 (20.1–128) | 0.72 | 68.7 (30.8–244) | 86.9 (26.9–246) | 0.70 |
|
| ||||||
| IL-12 | 2.7 (2.7–10.8) | 2.7 (2.7–6.6) | 0.0072 | 2.7 (2.7–10.8) | 2.7 (2.7–12.3) | 0.71 |
|
| ||||||
| Interferon-γ | 3.7 (2.7–12.3) | 2.7 (2.7–8.3) | 0.011 | 2.7 (2.7–8.2) | 2.7 (2.7–8.7) | 0.84 |
|
| ||||||
| Granulocyte macrophage-colony stimulating factor | 4.6 (2.7–10.2) | 3.5 (2.7–8.3) | 0.058 | 2.9 (2.7–8.3) | 2.7 (2.7–6.2) | 0.087 |
|
| ||||||
| Tumor necrosis factor-α | 5.4 (2.7–10.3) | 4.6 (2.7–8.3) | 0.038 | 9.9 (3.3–17.9) | 8.2 (2.7–15.6) | 0.018 |
IL = interleukin.
Values reported as median (interquartile range). All values are pg/mL. For the purposes of statistical analysis, undetectable cytokine levels were replaced with the minimum level of detectability for each assay, which was 2.7 pg/mL. Statistically significant p values are in bold font.