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. Author manuscript; available in PMC: 2016 Jan 15.
Published in final edited form as: Neurochem Int. 2007 Mar 4;50(0):983–997. doi: 10.1016/j.neuint.2007.02.008

Figure 1.

Figure 1

Proposed structure of the PT pore. CsA blocks pore opening by inhibiting the binding of cyclophilin D (CyP-D) to the adenine nucleotide translocator (ANT). VDAC, voltage-dependent anion channel; HK, hexokinase; CK, creatine kinase. Modified from Rama Rao et al., Metab. Brain Dis. 18, 113–127, 2003.