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. 2016 Jan 15;11(1):e0146094. doi: 10.1371/journal.pone.0146094

Fig 1. Effects of SB-710411 on ischemia/reperfusion injury-induced myocardial infarction in rats.

Fig 1

Evans Blue and 2,3,5-triphenyltetrazolium chloride (TTC) double staining was used to determine the ischemic size and infarction size. A. Rat myocardial slice stained by Evans blue and TTC. The normal area was stained blue, the area at risk (AAR) was stained red, and the area of infract size (IS) was stained pale white. a: Sham; b: Control; c: 1.6 mg/kg verapamil; d ~ f: 0.5, 1.0 and 2.0 μg/kg SB-710411. B. Effect of SB-710411 on the myocardial infarction. The IS was normalized by expressing it as a percentage of the AAR (IS/AAR). C. Effect of SB-710411 on the AAR. AAR was expressed as a percentage of the left ventricular area (AAR/LV). Results are expressed as mean ± SD (n = 8 per group). **p < 0.01 vs. the sham group; #p < 0.05, ##p < 0.01 vs. the control group.