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. 2016 Jan 15;11(1):e0146884. doi: 10.1371/journal.pone.0146884

Table 1. Effect of acetylshikonin on biochemical parameters of serum in HFD induced obese rats.

Normal HFD HFD+low AS HFD+middle AS HFD+high AS
TC (mM) 1.24±0.10 1.68±0.33* 1.48±0.28 1.38±0.25 1.64±0.28
LDL (mM) 0.25±0.03 0.58±0.19** 0.51±0.12 0.41±0.18 0.49±0.14
HDL (mM) 0.65±0.03 0.48±0.09** 0.45±0.09 0.45±0.09 0.51±0.08
TG (mM) 0.79±0.17 1.21±0.10*** 1.11±0.32 0.93±0.29# 0.73±0.27##
FFA (mM) 0.43±0.27 0.70±0.32** 0.62±0.29 0.51±0.41# 0.49±0.12##

TC, total cholesterol; LDL, low density lipoprotein cholesterol; HDL, high density lipoprotein cholesterol; TG, triglyceride; FFA, free fatty acid. Values are expressed as mean ± SE of 6 rats.

*P < 0.05

**P < 0.01

***P < 0.001 vs. normal group

#P < 0.05

##P < 0.01

###P < 0.001 vs. model group, significantly different from the HFD rats.