Table 1. Effect of acetylshikonin on biochemical parameters of serum in HFD induced obese rats.
Normal | HFD | HFD+low AS | HFD+middle AS | HFD+high AS | |
---|---|---|---|---|---|
TC (mM) | 1.24±0.10 | 1.68±0.33* | 1.48±0.28 | 1.38±0.25 | 1.64±0.28 |
LDL (mM) | 0.25±0.03 | 0.58±0.19** | 0.51±0.12 | 0.41±0.18 | 0.49±0.14 |
HDL (mM) | 0.65±0.03 | 0.48±0.09** | 0.45±0.09 | 0.45±0.09 | 0.51±0.08 |
TG (mM) | 0.79±0.17 | 1.21±0.10*** | 1.11±0.32 | 0.93±0.29# | 0.73±0.27## |
FFA (mM) | 0.43±0.27 | 0.70±0.32** | 0.62±0.29 | 0.51±0.41# | 0.49±0.12## |
TC, total cholesterol; LDL, low density lipoprotein cholesterol; HDL, high density lipoprotein cholesterol; TG, triglyceride; FFA, free fatty acid. Values are expressed as mean ± SE of 6 rats.
*P < 0.05
**P < 0.01
***P < 0.001 vs. normal group
#P < 0.05
##P < 0.01
###P < 0.001 vs. model group, significantly different from the HFD rats.