Table 3. Number of new and expected cases.
Age, y | 1 st-degree relative, n | Dilated aorta, n | 2nd-degree relative, n | Dilated aorta, n | Dilated aorta, total n |
18–30 | 10 | 0 | 18 | 1 | 1 |
30–39 | 10 | 1 | 19 | 3 | 4 |
40–49 | 13 | 6 | 11 | 0 | 6 |
50–59 | 11 | 5 | 1 | 0 | 5 |
60–69 | 10 | 3 | 1 | 0 | 3 |
70+ | 2 | 0 | 0 | 0 | 0 |
Total (expected) | 56 | 15 (28) | 50 | 4 (12.5) | 19 (40.5) |
The majority of individuals with dilatation of the aorta were found among first-degree relatives. The number of new cases (19) was significantly lower than would be expected for dominant inheritance (40).