Comparison of EMP and PMP levels between patients on hemodialysis and healthy participants after excluding patients with diabetes mellitus or hypertension. (A) MPs of 3 markers in patients without diabetes mellitus (n=41) were significantly higher than healthy participants (n=28). (B) The levels of CD31+CD42−EMP and CD31+CD42+PMP were significantly higher in normotensive patients on hemodialysis (n=15) compared with the controls (n=28). (C) When patients with diabetes mellitus and hypertension were excluded, levels of CD31+CD42−EMP and CD31+CD42+PMP were significantly higher in patients on hemodialsis (patients, n=8; controls, n=28). Data are expressed as means ±SEM. ⁎P<0.01 vs. control. ⁎⁎P<0.05 vs. control. EMP, endothelial microparticles; MP, microparticle; PMP, platelet-derived microparticles; SEM, standard error of mean.