Table 1.
Baseline Characteristics of HD Patients and Controlsa
| Variables | HD patients (n=82) | Healthy controls (n=28) | P |
|---|---|---|---|
| Sex (men, %) | 30 (36.6) | 18 (64.3) | 0.008 |
| Age (years) | 61.2±1.5 | 45.1±1.4 | <0.001 |
| Hypertension (%) | 67 (81.7) | 0 | |
| Diabetes (%) | 41 (50.0) | 0 | |
| Causes of ESRD (%) | 0 | ||
| Diabetes mellitus | 42 (51.2) | ||
| Hypertension | 26 (31.7) | ||
| Glomerulonephritis | 5 (6.1) | ||
| Other causes | 9 (11.0) | ||
| HD duration (years) | 4.0 (1.1–21.6) | 0 | |
| Usage of RAS blocker (%) | 34 (41.5) | 0 | |
| Usage of statin (%) | 10 (12.2) | 0 | |
| Usage of antiplatelet (%) | 38 (46.3) | ||
| HD access type (%) | 0 | ||
| AVF | 79 (96.3) | ||
| Kt/V | 1.46 (1.05–2.20) | ND | |
| nPCR (g/kg/day) | 1.06 (0.56–1.91) | ND | |
| BUN (mg/dL) | 69.5±2.1 | 13.3±0.6 | <0.001 |
| Creatinine (mg/dL) | 10.02±0.34 | 0.96±0.04 | <0.001 |
| Albumin (g/dL) | 3.59±0.07 | 4.51±0.04 | <0.001 |
| Total cholesterol (mg/dL) | 175.6±4.5 | 197.0±6.1 | 0.002 |
| LDL cholesterol (mg/dL) | 111.0±3.9 | 121.6±5.0 | <0.001 |
| Hemoglobin (g/dL) | 10.43±1.02 | 14.77±1.68 | <0.001 |
| Platelet (×103/μL) | 188.6±9.8 | 221.9±9.0 | 0.003 |
AVF, arteriovenous fistula; AVG, arteriovenous graft; BUN, blood urea nitrogen; ESRD, end-stage renal disease; HD, hemodialysis; LDL, low density lipoprotein; ND, not determined; nPCR, normalized protein catabolic rate; RAS, renin–angiotensin system; SEM, standard error of mean.
a
Data are presented as means±SEM or number (%).