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Paneth cell ablation in DK NEC is blocked by NRG4. A: Ileums from 14-day-old mice subjected to DK NEC, with or without NRG4, underwent staining by Alcian blue/periodic acid–Schiff (AB/PAS) and immunohistochemical analysis for lysozyme to identify Paneth cells (arrowheads). B: Paneth cells per crypt from five mice per condition (>50 crypts per mouse) were counted. Data are shown as means ± SEM. ∗P < 0.05, ∗∗P < 0.01.
