Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CD11b mediates tPA-induced macrophage migration. J774 macrophages were treated with 2.5 μg/mL control IgG or anti-CD11b neutralizing antibody (Ab) for 1 hour, followed by incubation with vehicle and 10 nmol/L tPA for 1 minute or 24 hours. A: Western blot for phospho-FAK (Tyr925) and α-tubulin. B: Quantitation of phospho-FAK abundance. C: Transwell motility assay. ∗P < 0.05, ∗∗P < 0.01. n = 3 (B); n = 5 (C).
