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. 2012 Mar;180(3):895–903. doi: 10.1016/j.ajpath.2011.11.030

Figure 2.

Figure 2

ASNS copy number is up-regulated in CRPC and is tightly correlated to its transcript and protein levels. Correlation of ASNS DNA copy number with mRNA (A) and protein (B) expression. C: ASNS mRNA correlation with protein expression. D: DNA copy number correlation of ASNS and AR. Chromosome 7 with the subfigure used to visualize the ASNS gene in our CRPC samples. The ASNS copy number values in all samples were larger than the threshold of 0.4. E: Different samples are shown using different colors. F: Hormone-sensitive prostate cancers from the Stanford data set (n = 45), showing ASNS copy number values in all samples <0.4 threshold. aCGH, array comparative genomic hybridization; cc, correlation co-efficient (Pearson); HSPC, hormone-sensitive prostate cancer.