Table 3.
Comparison of the Size of Hepatic Tumor in the Implantation Site between Different Groups of Cell Number
| Hepatic tumor | Cell number to implant and number of the mouse |
||
|---|---|---|---|
| 1.00 × 106 cells/20 μL (n = 6) | 0.50 × 106 cells/20 μL (n = 4) | 0.25 × 106 cells/20 μL (n = 2) | |
| Size of hepatic tumor at 12 weeks, mm, means ± SD (range) | 8.5 ± 4.7 (2–15) | 8.5 ± 4.5 (5–15) | (2, 2) |
| Tumor formation | |||
| Intrahepatic tumor, n/N (%) | |||
| Hepatic tumor in implantation site | 6/6 (100) | 4/4 (100) | 2/2 (100) |
| Satellite nodule | 6/6 (100) | 4/4 (100) | 2/2 (100) |
| Intrahepatic dissemination | 4/6 (66.7) | 2/4 (50) | 0/2 (0) |
| Extrahepatic tumor, n/N (%) | |||
| Peritoneum | 4/6 (66.7) | 2/4 (50) | 1/2 (50) |
| Other | 1/6 (16.7) | 0/4 (0) | 0/2 (0) |
| Regional lymph node of the stomach | |||