Table 2.

Scoring of Cellular Dipeptidyl Peptidase 4 Immunostaining in Lung Cell Types

Cell	Unaffected	COPD	CF	P value∗
Group age, mean (range), years	23 (0.2–53)	57 (32–68)	34 (19–76)	0.048
Ciliated cells	1.6 ± 0.2 (n = 16)	1.5 ± 0.3 (n = 4)	1.4 ± 0.2 (n = 8)	0.74
Goblet cells	1.8 ± 0.2 (n = 16)	2.3 ± 0.3 (n = 4)	1.5 ± 0.2 (n = 8)	0.99
Nonciliated	1.4 ± 0.2 (n = 16)	2.5 ± 0.3 (n = 4)	1.3 ± 0.2 (n = 8)	0.53
Type II cells	4.1 ± 0.2 (n = 16)	5.0 ± 0.0 (n = 4)	4.5 ± 0.2 (n = 8)	0.014
Type I cells	1.8 ± 0.2 (n = 16)	2.5 ± 0.3 (n = 4)	2.6 ± 0.2 (n = 8)	0.012
SMG, serous	5.0 ± 0.0 (n = 13)	5.0 ± 0.0 (n = 4)	5.0 ± 0.0 (n = 5)	>0.99
SMG, mucous	2.0 ± 0.2 (n = 13)	2.0 ± 0.4 (n = 4)	1.4 ± 0.2 (n = 5)	0.33
Alveolar macrophages	4.2 ± 0.2 (n = 16)	4.8 ± 0.3 (n = 4)	4.8 ± 0.2 (n = 8)	0.03

CF, cystic fibrosis; COPD, chronic obstructive pulmonary disease; SMG, submucosal gland.

^∗Mann-Whitney U-test comparing group 1 (unaffected) and group 2 (COPD and CF). Bold text indicates P < 0.05.