FIG. 2.

Genotoxicity in D1 cells exposed to As⁺³ or PARP inhibitor (DPQ). D1 cells were treated with 5, 50, or 500 nM As⁺³ for 4 and 18 h. A, DNA damage was measured by percentage of DNA in tail using alkaline Comet assay. B, PARP activities were measured with Trevigen ELISA kit represented by absorbance at 450 nm. C and D, DNA damage were measured by alkaline Comet assay in D1 cells treated with 5, 50, and 500 nM As⁺³ and 0.1, 1, and 10 µM PARP inhibitor, DPQ for 4 h (C) and 18 h (D). *Significantly different compared to control (P < .05). Results are means ± SD.