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. Author manuscript; available in PMC: 2017 Jan 12.
Published in final edited form as: Cell Metab. 2016 Jan 12;23(1):27–47. doi: 10.1016/j.cmet.2015.12.006

Figure 4. Use of glycolysis/TCA cycle intermediates for biosynthesis and NADH production.

Figure 4

a, differences in the central carbon metabolism of a cell in a quiescent state compared to a proliferating cell; b, diverse biosynthetic outputs of central carbon metabolism. RTK, receptor tyrosine kinase; GLUT1, glucose transporter 1; PKM2, pyruvate kinase M2; ACSS2, acetyl-CoA synthetase 2; LDH-A, lactate dehydrogenase A; PDH, pyruvate dehydrogenase; PDK1, pyruvate dehydrogenase kinase 1; ACLY, ATP-citrate lyase; MCT1, monocarboxylate transporter 1; ASCT2/SN2, glutamine transporter.