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. 2015 Dec 1;2015(12):CD010472. doi: 10.1002/14651858.CD010472.pub2

Birt 1998.

Methods Study design: parallel‐group randomized controlled trial
Number randomized: 43 eyes of 43 participants total;
11 participants in trabeculectomy + MMC + Gelfilm® (Pfizer) group;
7 participants in trabeculectomy + MMC group;
11 participants in trabeculectomy + Gelfilm® (Pfizer) group;
14 participants in trabeculectomy group
Exclusions after randomization: none reported
Losses to follow‐up: none reported
Unit of analysis: individual (1 eye per participant)
 Number analyzed: 43 participants total;
11 participants in trabeculectomy + MMC + Gelfilm® (Pfizer) group;
7 participants in trabeculectomy + MMC group;
11 participants in trabeculectomy + Gelfilm® (Pfizer) group;
14 participants in trabeculectomy group
How were missing data handled?: no missing data
Power calculation: not reported
Participants Country: not reported
 Mean age: not reported
 Gender: not reported
 Inclusion criteria: not reported
 Exclusion criteria: not reported
Equivalence of baseline characteristics: not reported
Interventions Intervention 1: trabeculectomy + MMC + Gelfilm® (Pfizer)
 Intervention 2: trabeculectomy + MMC
 Intervention 3: trabeculectomy + Gelfilm® (Pfizer)
 Intervention 4: trabeculectomy
Length of follow‐up:
Planned: not reported
 Actual: 1 year
Outcomes Primary and secondary outcomes not distinguished
Outcomes, as reported: postoperative IOP, use of postoperative 5‐FU, and complications
Intervals at which outcomes assessed: 1 year
Notes Publication type: published abstract
Funding sources: not reported
Disclosures of interest: not reported
Trial registry: not registered
Study period: not reported
Subgroup analyses: none reported
Publication language: English
Attempted to contact author, but unable to find contact information in abstract
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Random sequence generation was not reported
Allocation concealment (selection bias) Unclear risk Allocation concealment was not reported
Masking of participants and personnel (performance bias) Unclear risk Masking of participants and personnel was not reported
Masking of outcome assessment (detection bias) High risk Outcome assessors not masked as devices can be seen during eye examination
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All participants completed 1‐year follow‐up
Selective reporting (reporting bias) Unclear risk The protocol was not available and the authors did not define which outcomes and complications they were going to report
Other bias Unclear risk Did not report source of funding or conflict of interest
The abstract did not have enough information