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. 2015 Dec 1;2015(12):CD010472. doi: 10.1002/14651858.CD010472.pub2

Yan 2004.

Methods Study design: parallel‐group randomized controlled trial (11 participants both eyes included)
Number randomized: 63 eyes of 52 participants total;
36 eyes of 28 participants in trabeculectomy + AMT group;
27 eyes of 24 participants in trabeculectomy group
Exclusions after randomization: none reported
Losses to follow‐up: none reported
Unit of analysis: eye
Number analyzed: 63 eyes of 52 participants total;
36 eyes of 28 participants in trabeculectomy + AMT group;
27 eyes of 24 participants in trabeculectomy group
How were missing data handled?: no missing data
Power calculation: not reported
Participants Country: China
Mean age: mean age not reported; age range 45 to 76 years; not reported by intervention group
Gender: 25/52 (48%) men and 27/52 (52%) women overall; not reported by intervention group
Inclusion criteria: PACG
Exclusion criteria: not specified
Equivalence of baseline characteristics: yes
Interventions Intervention 1: trabeculectomy + AMT
Intervention 2: trabeculectomy
Length of follow‐up:
Planned: not reported
 Actual: 6 months
Outcomes Primary and secondary outcomes not distinguished
Outcomes, as reported: depth of anterior chamber, IOP, visual acuity, filtering bleb, surgical success, complications
Intervals at which outcomes assessed: 1 day, 1 week, 2 weeks, and 1, 3, and 6 months
Notes Publication type: published article
Funding sources: not reported
Disclosures of interest: not reported
Trial registry: not registered
Study period: not reported
Subgroup analyses: none reported
Publication language: Chinese
Authors not contacted
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Random sequence generation was not reported
Allocation concealment (selection bias) Unclear risk Allocation concealment was not reported
Masking of participants and personnel (performance bias) Unclear risk Masking of participants and personnel was not reported
Masking of outcome assessment (detection bias) High risk It is not possible to mask outcome assessors, as devices can be seen during eye examination
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk The number of participants with missing or incomplete outcome assessment was not reported
Selective reporting (reporting bias) High risk Protocol was not available. Surgical success and visual acuity were reported in the Results section, but were not mentioned in the Methods section
Other bias Unclear risk Did not report source of funding or conflict of interest. This article provided nothing on study design; we contacted the authors but did not receive a response