Yan 2004.
Methods |
Study design: parallel‐group randomized controlled trial (11 participants both eyes included) Number randomized: 63 eyes of 52 participants total; 36 eyes of 28 participants in trabeculectomy + AMT group; 27 eyes of 24 participants in trabeculectomy group Exclusions after randomization: none reported Losses to follow‐up: none reported Unit of analysis: eye Number analyzed: 63 eyes of 52 participants total; 36 eyes of 28 participants in trabeculectomy + AMT group; 27 eyes of 24 participants in trabeculectomy group How were missing data handled?: no missing data Power calculation: not reported |
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Participants |
Country: China Mean age: mean age not reported; age range 45 to 76 years; not reported by intervention group Gender: 25/52 (48%) men and 27/52 (52%) women overall; not reported by intervention group Inclusion criteria: PACG Exclusion criteria: not specified Equivalence of baseline characteristics: yes |
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Interventions |
Intervention 1: trabeculectomy + AMT Intervention 2: trabeculectomy Length of follow‐up: Planned: not reported Actual: 6 months |
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Outcomes | Primary and secondary outcomes not distinguished Outcomes, as reported: depth of anterior chamber, IOP, visual acuity, filtering bleb, surgical success, complications Intervals at which outcomes assessed: 1 day, 1 week, 2 weeks, and 1, 3, and 6 months |
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Notes |
Publication type: published article Funding sources: not reported Disclosures of interest: not reported Trial registry: not registered Study period: not reported Subgroup analyses: none reported Publication language: Chinese Authors not contacted |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Random sequence generation was not reported |
Allocation concealment (selection bias) | Unclear risk | Allocation concealment was not reported |
Masking of participants and personnel (performance bias) | Unclear risk | Masking of participants and personnel was not reported |
Masking of outcome assessment (detection bias) | High risk | It is not possible to mask outcome assessors, as devices can be seen during eye examination |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | The number of participants with missing or incomplete outcome assessment was not reported |
Selective reporting (reporting bias) | High risk | Protocol was not available. Surgical success and visual acuity were reported in the Results section, but were not mentioned in the Methods section |
Other bias | Unclear risk | Did not report source of funding or conflict of interest. This article provided nothing on study design; we contacted the authors but did not receive a response |