Table 2.
Expression of known crustacean neuromodulators and neurotransmitters in the Homarus americanus transcriptome
| Neuromodulator | Function | Count | DE | Up | Down |
|---|---|---|---|---|---|
| 5-HT | 5-HT receptor | 17 | 4 | 4 | 0 |
| 5-HT | 5-HT transporter | 3 | 1 | 1 | 0 |
| Acetylcholine | ACH receptor | 35 | 13 | 13 | 0 |
| Acetylcholine | ACH transporter | 3 | 2 | 2 | 0 |
| Angiotensin | Angiotensin | 16 | 7 | 1 | 6 |
| AST | AST | 5 | 4 | 4 | 0 |
| AST | AST receptor | 2 | 0 | 0 | 0 |
| Callisulfakinin | Callisulfakinin | 1 | 0 | 0 | 0 |
| CCAP | CCAP | 1 | 1 | 1 | 0 |
| CCAP | CCAP receptor | 2 | 1 | 1 | 0 |
| Dopamine | Conversion of dopamine to noradrenaline | 2 | 2 | 2 | 0 |
| Dopamine | Dopamine receptor | 6 | 3 | 3 | 0 |
| Dopamine | Dopamine transporter | 2 | 0 | 0 | 0 |
| FLRFamide | FLRFamide | 3 | 1 | 1 | 0 |
| FMRFamide | FMRFamide receptor | 7 | 1 | 1 | 0 |
| FMRFamide | FMRFamide-related neuropeptide | 5 | 2 | 2 | 0 |
| GABA | GABA receptor | 22 | 4 | 0 | 4 |
| GABA | GABA transporter | 12 | 10 | 7 | 3 |
| Glutamate | Excitatory amino acid transporter | 11 | 5 | 5 | 0 |
| Glutamate | Glutamate receptor | 126 | 52 | 37 | 15 |
| Glutamate | Glutamate transporter | 11 | 6 | 6 | 0 |
| HCNP | HCNP | 1 | 1 | 1 | 0 |
| Myomodulin | Myomodulin | 1 | 1 | 0 | 1 |
| NO | Nitric-oxide (NO) synthesis regulation | 29 | 11 | 5 | 6 |
| Octopamine | Octopamine receptor | 5 | 0 | 0 | 0 |
| Orcokinin | Orcokinin | 5 | 2 | 2 | 0 |
| Prohormone-1 | Brain peptide SYWKQCAFNAVSCF-amide | 1 | 1 | 1 | 0 |
| RPCH | RPCH | 1 | 1 | 1 | 0 |
| SIFamide | SIFamide receptor | 1 | 0 | 0 | 0 |
| Substance K | Substance-K receptor | 1 | 0 | 0 | 0 |
| Tachykinin | Tachykinin | 1 | 1 | 1 | 0 |
| Tachykinin | Tachykinin receptor | 5 | 3 | 3 | 0 |
Transcripts manually curated into functional categories by their annotations. Count is the number of transcripts mapping to a function; DE indicates the number of transcripts differentially expressed in nervous system tissues compared to muscle tissues (adj p < 0.05); up and down signify the number of DE transcripts upregulated (positive log2fold change) or downregulated (negative log2fold change), respectively