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. 2016 Jan 16;16:23. doi: 10.1186/s12885-016-2055-1

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© Dutta et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 10 — 2c treatment causes declination of Proteasome degradation pathway. HT-29 cells were treated with 2c and then subjected to measure three subtypes of proteasomal activities. As shown in figure there is a gradual time dependent decrease in the proteasomal activities i.e. downregulation of (a) chymotrypsin-like, (b) trypsin-like and (c) caspase-like enzyme activities occurs with respect to control according to different time intervals (12, 24, 48 h). Values are mean ± S.D and represent at least three experiments (**P <0.05 compared to control)