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. 2016 Jan 16;17:35. doi: 10.1186/s12859-016-0885-0

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© Acuña et al. 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — TRN obtained for a reduced set of co-regulated genes $C^{'}$ and the a priori graph $G_{A}$ . All the arcs were predicted by LOMBARDE. The arcs drawn in solid lines have been validated experimentally, although this information was not used in the prediction. The gene purC was co-expressed with metF, metA, and metQ; metN was co-expressed with purE and pyrD; metQ was co-expressed with codA; clcB was co-expressed with ydfN; and agaS was co-expressed with ugpA