Table 3 . Association between different scleroderma patterns and clinical or laboratory features .

Features	Scleroderma pattern
	Early pattern n (%)	Active pattern n (%)	Late pattern n (%)	Non-specific pattern n (%)	p
		Symptoms and signs, %
Fever	1(16.7%)	3(50%)	1(16.7%)	1(16.7%)	0.20
Heliotrope rash	0	6(50%)	4(33.3%)	2(16.7%)	1
Gottron papules	1(4.3%)	8(34.8%)	11(47.8%)	3(13%)	1
Gottron's sign	0	8(42.1%)	10(52.6%)	1(5.3%)	0.56
V sign	1(4.3%)	2(28.6%)	3(42.9%)	1(14.3%)	0.76
Shawl sign	0	2(66.7%)	1(33.3%)	0	0.41
Preorbital edema	1(16.7%)	2(33.3%)	2(33.3%)	1(16.7%)	0.53
Calcification	0	5(50%)	4(40%)	1(10%)	0.60
Mechanic hand	1(8.3%)	4(33.3%)	6(50%)	1(8.3%)	0.60
Facial erythema	1(16.7%)	7(46.7%)	6(40%)	1(6.7%)	0.06
Arthritis	1(25%)	1(25%)	1(25%)	1(25%)	0.71
Polyarthralgia	1(16.7%)	7(46.7%)	6(40%)	1(6.7%)	0.06
ILD*	0	3(33.3%)	4(44.4%)	2(22.2%)	0.41
Dysphasia	0	3(37.5%)	4(50%)	1(12.5%)	1
Muscle weakness	0	9(45%)	9(45%)	2(10%)	0.56
		Laboratory findings, %
CK†	25%	17.9%	7.1%	50%	0.29
ESR‡	1(5.5%)	8(44.5%)	7(38.9%)	2(11.1%)	0.16
CRP§	0	2(40%)	2(40%)	1(20%)	1
ANA||	1(7.7%)	5(38.5%)	7(53.8%)	0	0.11
Anti RO antibody	0	0	4(100%)	0	0.46
Anti JO1 antibody	0	2(50%)	2(50%)	0	0.71
Myopathic EMG¶	1(5.3%)	9(47.3%)	8(42.1%)	1(5.3%)	0.015

*ILD: Interstitial lung disease, †CK: creatine kinase, ‡ESR: Erythrocyte sedimentation rate. A level of >12 in male and >18 in female was considered abnormal [52]. §CRP: C-Reactive Protein. A level of >5 mg/L was considered as abnormal.

||ANA: Antinuclear antibody, ¶EMG: electromyography