Table 2. List of differentially expressed miRNAs of MSC from young and aged donors cultured under hypoxic (Hx) culture condition relative to normal (nx) culture condition.

miRNA of young MSC	Fold change >2 (Hx/nx)	p-value
mir-210	13.64	0.0119
mir-423	2.58	0.0105
mir-1468	2.30	0.0243
mir-21	2.26	0.0197
mir-3605	2.21	0.0061
mir-625	2.20	0.0709
mir-155	2.08	0.0071
mir-3065	2.07	0.0082
mir-138-1	2.06	0.0034
mir-424	−2.85	0.0073
let-7i	−3.22	0.0038
mir-655	−3.67	0.0323
mir-33a	−4.15	0.0182
miRNA of aged MSC	Fold change >2 (Hx/nx)	p-value
mir-7977	2.55	0.0350
mir-195	2.15	0.0061
mir-19b	−2.58	0.0280
mir-21	−2.61	0.0089
mir-99a	−2.74	0.0168
mir-708	−3.17	0.0030
mir-1185-1	−3.23	0.0048
mir-590	−3.24	0.0102
mir-455	−3.46	0.0039
mir-374a	−3.53	0.0315
mir-381	−3.53	0.0340
mir-126	−3.87	0.0019
mir-196a-2	−3.99	0.0340
mir-136	−4.03	0.0081
mir-100	−4.29	0.0062
mir-34b	−4.33	0.0159
mir-542	−4.35	0.0277
mir-376a-1	−4.35	0.0307
mir-1197	−4.53	0.0053
let-7f-2	−4.69	0.0045
mir-1228	−4.70	0.0091
mir-2355	−4.73	0.0143
mir-148b	−4.79	0.0729
mir-33a	−4.84	0.0295
mir-551b	−4.88	0.0013
mir-483	−6.29	0.0061
mir-29a	−6.40	0.0003
mir-378a	−6.56	0.0114
mir-376b	−8.12	0.0039
mir-561	−8.28	0.0006
mir-29b-1//mir-29b-2	−9.30	0.0340
mir-193a	−11.88	0.0315
mir-627	−15.00	0.0483

Note:

(P < 0.05) with at least two-fold change.