Table 2. The 10 most highly expressed immune genes in the Tasmanian devil milk transcriptome.
Transcript Id | Gene | Protein | Relative percentagea | Immune function | |
---|---|---|---|---|---|
1 | comp62784 | LYZ | Lysozyme C | 3.58 | Defence again bacteria, inflammatory response. Important part of innate immunity (Nicholas et al., 1989) |
2 | comp129481 | WAP | Whey acidic protein | 1.50 | Potential protease inhibitor (Nicholas et al., 1997) |
3 | comp62802 | FTH1 | Ferritin heavy subunit | 0.30 | Iron storage and sequestering iron (Brock, 1980; Demmer et al., 1999) |
4 | comp129487 | FTL | Ferritin light subunit | 0.21 | Iron storage and sequestering iron (Brock, 1980; Demmer et al., 1999) |
5 | comp129504 | AZGP1 | Zinc-alpha-2-glycoprotein | 0.08 | Potential role antigen binding (Sanchez, López-Otín & Bjorkman, 1997) |
6 | comp129394 | MHC I | Major histocompatibility complex class I | 0.07 | Binds to antigens and stimulation of the immune response (Chaplin, 2010) |
7 | comp129498 | S100A9 | S100 calcium binding protein A9 | 0.07 | Important regulatory roles in inflammatory immune response. It can induce neutrophil chemotaxis and adhesion and promote phagocytosis (Ryckman et al., 2003) |
8 | comp62779 | CLC25 | Chemokine (C-C motif) ligand 25 | 0.06 | CCL25 induces chemotaxis of thymocytes, macrophages, and dendritic cells (Vicari et al., 1997) |
9 | comp129492 | TPT1 | Translationally-controlled tumour protein | 0.04 | TCTP is involved in microtubule stabilization, calcium-binding activities, and apoptosis (Bommer & Thiele, 2004) |
10 | comp127370 | B2M | β-2-microglobulin | 0.04 | β-chain of MHC I: serum protein associated with major MHC I heavy chain (Adamski & Demmer, 1999; Gussow et al., 1987) |
Notes.
Relative percentage: the gene expression as a percentage of the total gene expression of the entire transcriptome.