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. 2016 Jan 12;4:e1569. doi: 10.7717/peerj.1569

Table 2. The 10 most highly expressed immune genes in the Tasmanian devil milk transcriptome.

Transcript Id Gene Protein Relative percentagea Immune function
1 comp62784 LYZ Lysozyme C 3.58 Defence again bacteria, inflammatory response. Important part of innate immunity (Nicholas et al., 1989)
2 comp129481 WAP Whey acidic protein 1.50 Potential protease inhibitor (Nicholas et al., 1997)
3 comp62802 FTH1 Ferritin heavy subunit 0.30 Iron storage and sequestering iron (Brock, 1980; Demmer et al., 1999)
4 comp129487 FTL Ferritin light subunit 0.21 Iron storage and sequestering iron (Brock, 1980; Demmer et al., 1999)
5 comp129504 AZGP1 Zinc-alpha-2-glycoprotein 0.08 Potential role antigen binding (Sanchez, López-Otín & Bjorkman, 1997)
6 comp129394 MHC I Major histocompatibility complex class I 0.07 Binds to antigens and stimulation of the immune response (Chaplin, 2010)
7 comp129498 S100A9 S100 calcium binding protein A9 0.07 Important regulatory roles in inflammatory immune response. It can induce neutrophil chemotaxis and adhesion and promote phagocytosis (Ryckman et al., 2003)
8 comp62779 CLC25 Chemokine (C-C motif) ligand 25 0.06 CCL25 induces chemotaxis of thymocytes, macrophages, and dendritic cells (Vicari et al., 1997)
9 comp129492 TPT1 Translationally-controlled tumour protein 0.04 TCTP is involved in microtubule stabilization, calcium-binding activities, and apoptosis (Bommer & Thiele, 2004)
10 comp127370 B2M β-2-microglobulin 0.04 β-chain of MHC I: serum protein associated with major MHC I heavy chain (Adamski & Demmer, 1999; Gussow et al., 1987)

Notes.

a

Relative percentage: the gene expression as a percentage of the total gene expression of the entire transcriptome.