Figure 1.

Effects of nicotine on task‐associated (see Methods for task definition) neuronal response in the left VPC. A significant drug X diagnosis interaction was observed. For visualization, statistical parametric maps are displayed in the neurologic convention (R on R) and thresholded at P < 0.01, cluster extent (k) > 50 voxels. Error bars represent the standard error. **Significant diagnosis X treatment interaction. Hum Brain Mapp 00:000–000, 2014. [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]