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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Ann Hum Genet. 2015 Nov 15;80(1):63–80. doi: 10.1111/ahg.12137

Figure 11. Manhattan plot for score test of the SAFHS data.

Figure 11

Results from the three degrees of freedom test for NIMA or offspring effects (β10, β.1, β.2) using the score test adjusting for age and sex. Data from the SAFHS consists of 635,494 SNPs from 419 offspring with HDL measurements in 43 multi-generational families. A dashed horizontal line is drawn at the initial significance cutoff for an FDR of 10%.