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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Thromb Haemost. 2015 Dec 11;14(1):153–166. doi: 10.1111/jth.13181

Figure 1. TF expression on tumor cells, tumor cell-derived microvesicles and tumors.

Figure 1

(A) Cellular tissue factor (TF) activity was measured using a one stage clotting assay. *P<0.001, n=6. (B) BxPc-3 and L3.6pl MVs were imaged by transmission electron microscopy. (C) Microvesicle (MV) TF activity was measured using a two-stage clotting assay. *P<0.005, n=4. TF activity was normalized to total protein. (D) TF antigen expression on MVs was analyzed by MV flow cytometry. Representative histograms are shown and the mean fluorescence intensity (MFI) of an anti-TF antibody is reported. Data were analyzed by unpaired student’s t-test. (E) Human TF expression in BxPc-3 and L3.6pl orthotopic tumors from mice.

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