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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Genes Brain Behav. 2015 Oct 20;14(8):635–640. doi: 10.1111/gbb.12254

Table 3.

ZNF804A two-SNP haplotype associations with heroin addiction.

rs7597593- rs1344706 haplotype European Americans (N=711 cases and 6,384 controls) African Americans (N=1,293 cases and 2,369 controls) Meta-analysis
Frequency (%) P OR (95% CI) Frequency (%) P OR (95% CI) P OR (95% CI)
T-A 38.3 0.0064 1.20 (1.05–1.37) 63.5 0.39 1.08 (0.90–1.30) 0.0066 1.16 (1.04–1.29)
C-A 22.9 0.55 1.05 (0.90–1.22) 28.1 0.14 1.16 (0.95–1.40) 0.16 1.09 (0.97–1.23)
C-C or T-C 38.8 Reference 8.5 Reference Reference

CI, confidence interval; OR, odds ratio