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. Author manuscript; available in PMC: 2016 Nov 18.
Published in final edited form as: Adv Healthc Mater. 2015 Jul 30;4(16):2475–2487. doi: 10.1002/adhm.201500236

Figure 1.

Figure 1

Methods of Fabricating ECM-Based Biohybrid Materials. (A) Materials are fabricated with interwoven fibers, using either electrospinning, electrospraying, or a combination of the two. (B) Materials are fabricated by blending hydrogel components of ECM derived proteins and polymer chains. (C) Materials are built using a layering technique, with either a whole tissue or a polymer scaffold as a base. (D) Cell-built ECM layer fabrication, where cells are cultured on a polymer scaffold, and then removed, leaving an ECM layer on the polymer surface.