Table 2.
Features associated with RBDSQ Cut-scores in Parkinson disease
| RBDSQ+ | RBDSQ- | P | |
|---|---|---|---|
|
| |||
| LRRK2-PD (n=142) | 28 (19.7%) | 114 (80.3%) | --- |
| Women | 9 (32.1%) | 56 (49.1%) | 0.14 |
| Age | 68.2 ± 9.1 | 67.0 ± 10.0 | 0.72 |
| Duration | 14.6 ± 7.6 | 8.8 ± 6.5 | <0.01 |
| UPSIT Score (125) | 20.9 ± 8.6 | 23.5 ± 8.6 | 0.19 |
| Hyposmia | 15 (60.0%) | 53 (53.0%) | 0.53 |
| UPDRS-III (135) | 24.2 ± 12.9 | 20.3 ± 13.1 | 0.07 |
| PIGD phenotype (133) | 22 (81.5%) | 67 (63.2%) | 0.11 |
| MoCA Score (131) | 24.8 ± 3.6 | 25.4 ± 2.8 | 0.67 |
| STAI (42) | |||
| State | 43.4 ± 11.8 | 33.7 ± 13.4 | 0.03 |
| Trait | 48.8 ± 14.6 | 33.4 ± 11.7 | <0.01 |
|
| |||
| IPD (n=144) | 44 (30.6%) | 100 (69.4%) | --- |
|
| |||
| Women | 11 (25.0%) | 40 (40.0%) | 0.08 |
| Age | 67.5 ± 10.1 | 63.8 ± 11.7 | 0.06 |
| Duration | 7.8 ± 6.6 | 7.2 ± 7.9 | 0.48 |
| UPSIT Score (117) | 17.1 ± 7.6 | 19.5 ± 6.9 | <0.05 |
| Hyposmia | 26 (86.7%) | 65 (74.1%) | 0.21 |
| UPDRS-III (142) | 21.2 ± 12.0 | 19.7 ± 11.8 | 0.51 |
| PIGD phenotype (141) | 31 (70.5%) | 45 (46.4%) | <0.01 |
| MoCA Score (134) | 24.7 ± 3.2 | 25.1 ± 3.9 | 0.28 |
| STAI (36) | |||
| State | 40.2 ± 7.1 | 34.6 ± 10.5 | 0.06 |
| Trait | 38.6 ± 9.8 | 36.9 ± 12.6 | 0.48 |
Values provided are number (%) or mean ± SD, as appropriate, unless otherwise stated.
RBD+=total RBDSQ score ≥5 (non-PD) and total RBDSQ score ≥6 (PD).; LRRK2-PD = LRRK2 G2019S mutation carriers with PD; IPD = idiopathic PD; UPSIT = University of Pennsylvania Smell Identification Test; Hyposmic = UPSIT percentile score < 15; UPDRS-III = Unified Parkinson Disease Rating Scale Motor Score; PIGD = Postural Instability and Gait Disorder subtype; MoCA = Montreal Cognitive Assessment; STAI = State-Trait Anxiety Inventory