Table 2.
Characteristics of the chronic liver disease patient groups with and without clinically significant fibrosis.
| Variable | No or mild fibrosis (n=10) | Significant fibrosis (n=6) |
|---|---|---|
| Fibrosis score (number of patients) | ||
| F0 | 6 | 0 |
| F1 | 4 | 0 |
| F2 | 0 | 2 |
| F3 | 0 | 2 |
| F4a | 0 | 2 |
| Inflammation score (number of patients) | ||
| A0 | 1 | 0 |
| A1 | 5 | 0 |
| A2 | 4 | 3 |
| A3 | 0 | 1 |
| Steatosis score (number of patients) | ||
| 0 | 8 | 2 |
| 1 | 1 | 2 |
| 2 | 1 | 0 |
| Mean age (SD) (years) | 55.1 (7.2) | 61.7 (4.1) |
| Mean BMI (SD) (kg/m2) | 28.1 (3.2) | 27.5 (2.2) |
| Mean AST (SD) (IU/L) | 45.9 (22.6) | 121.2 (175.9) |
| Mean ALT (SD) (IU/L) | 73.5 (48.1) | 125.2 (156.8) |
| Mean platelet count (SD) (109/L) | 197 (55) | 168 (47) |
| Mean total bilirubin (SD) (mg/dL) | 0.8 (1.3) | 0.7 (0.5) |
| Mean albumin (SD) (g/dL) | 4.55 (0.25) | 4.20 (0.40) |
| Mean AST/ALT ratio (SD) | 0.69 (0.21) | 0.87 (0.15) |
| Mean APRI (SD) | 0.66 (0.41) | 2.26 (3.52) |
| Mean MPF histogram mode (SD) (%)b | 5.94 (0.26) | 6.49 (0.36) |
a
Score is assigned to cirrhosis patients without biopsy based on the clinical diagnosis.
b
Values are significantly different according to Mann-Whitney U test (P=0.002)