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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Allergy Clin Immunol. 2015 Jul 17;137(1):137–146. doi: 10.1016/j.jaci.2015.05.042

Fig 1. Increased reactive oxygen species and Top scored gene network in the comparison NSAID-LTP-A vs. LTP-A.

Fig 1

A) Serum levels of free radicals (reactive oxygen species, ROS, and reactive nitrogen species, RNS) in the indicated groups. Data are expressed as mean±SEM. **p<.01, ***p<.001 compared to HV. B) Functional relationships of differentially expressed genes in NSAID-LTP-A vs. LTP-A in the top scored network “Cell death and Survival, Inflammatory response, Cancer”. The intensity of the node color indicates the degree of up-regulation (red) or down-regulation (green). Genes in uncolored nodes were of relevance for this network and integrated into the computationally generated networks on the basis of the evidence stored in the IPA knowledge memory, but they were not identified as differentially expressed. Lines indicate molecular interactions.