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. Author manuscript; available in PMC: 2016 Jan 16.
Published in final edited form as: J Cutan Pathol. 2015 Sep 2;42(11):807–814. doi: 10.1111/cup.12564

Fig. 4.

Fig. 4

Histogram showing the distribution of immunohistochemical staining scores for 5-hydroxymethycytosine (5-hmC) expression for melanocytic nevi and melanoma. An immunohistochemical staining score of zero (0) indicates no 5-hmC immunolabeling in any of the evaluable lesional nuclei, where an immunohistochemical staining score of 100 indicates that all lesional nuclei were markedly/strongly immunoreactive (see Methods for detailed description for calculating immunohistochemical staining score). When the two cohorts were evaluated separately, (A) and (B) respectively, the potential discriminatory ability of 5-hmC immunohistochemistry between nevi and melanoma is more evident than when both cohorts are combined (C).