Table 3.
Table showing mean ± SE cell counts from mice undergoing three episodes of defeat or control conditions. Data are shown through the ventral-dorsal extent of VTA and SNc.
| Region and Count | Male Control | Male Stress | Female Control | Female Stress |
|---|---|---|---|---|
| Ventral SN TH | 142.6 ± 12.6 | 130.1 ± 15.4 | 155.3 ± 35.0 | 174.7 ± 23.8 |
| Middle SN TH | 165.7 ± 25.3 | 163.4 ± 27.1 | 172.5 ± 28.8 | 177.1 ± 23.0 |
| Dorsal SN TH | 133.0 ± 27.9 | 151.4 ± 29.6 | 139.0 ± 22.7 | 134.0 ± 16.4 |
| Ventral SN c-fos | 10.3 ± 2.8 | 13.0 ± 4.5 | 7.0 ± 2.0 | 9.0 ± 1.7 |
| Middle SN c-fos | 13.0 ± 2.2 | 9.1 ± 2.8 | 13.3 ± 4.6 | 8.6± 1.9 |
| Dorsal SN c-fos | 6.6 ± 2.4 | 6.6 ± 2.1 | 7.5 ± 1.9 | 6.3 ± 1.9 |
| Ventral SN TH/c-fos | 1.00± 0.5 | 1.8 ± 0.6 | 2.8 ± 1.4 | 2.1 ± 0.9 |
| Middle SN TH/c-fos | 0.8 ± 0.5 | 0.7 ± 0.2 | 2.5 ± 1.0 | 1.0 ± 0.5 |
| Dorsal SN TH/c-fos | 1.4 ± 1.3 | 2.0 ± 0.9 | 2.0 ± 1.1 | 0.9± 0.7 |
| Ventral VTA TH | 60.9 ± 6.0 | 56.2 ± 7.7 | 66.9 ± 9.3 | 94.2 ± 6.9* |
| Middle VTA TH | 83.9 ± 19.2 | 77.1 ± 17.9 | 92.4 ± 12.4 | 102.5 ± 9.2 |
| Dorsal VTA TH | 63.5 ± 6.5 | 49.3 ± 5.7 | 74.7 ± 10.7 | 104.1 ± 11.2+ |
| Ventral VTA c-fos | 9.6 ± 2.9 | 11.3 ± 2.9 | 8.0 ± 4.6 | 8.7 ± 1.4 |
| Middle VTA c-fos | 21.1 ± 4.2 | 21.9 ± 5.6 | 27.0 ± 6.1 | 8.3 ± 1.5* |
| Dorsal VTA c-fos | 19.6 ± 5.7 | 31.0 ± 8.3 | 23.9 ± 9.3 | 11.1 ± 4.2 |
| Ventral VTA TH/c-fos | 5.6 ± 2.1 | 6.4 ± 3.1 | 2.0 ± 0.8 | 5.6 ± 1.0* |
| Middle VTA TH/c-fos | 10.5 ± 3.7 | 9.1 ± 4.9 | 17.0 ± 6.4 | 5.4 ± 1.3 |
| Dorsal VTA TH/c-fos | 12.5 ± 4.4 | 5.8 ± 2.3 | 12.0 ± 5.1 | 8.1 ± 2.9 |
*
p < 0.05 vs female control,
+
p = 0.06 vs female control