Table 4.
Candidate variants with P-values from 3 statistical tests performed on the complete discovery sample.
| Variant | Gene | Chr | Position(bp)a | N | MAFb | TDT | ASSOC | famSKAT |
|---|---|---|---|---|---|---|---|---|
| rs79762465 | FSIP2 | 2 | 186654867 | 502 | 0.041 | 1.5×10−8 | 1.2×10−5 | 2.0 × 10−5 |
| rs981782 | HCN1 | 5 | 45285718 | 403 | 0.462 | NA | 0.21 | 2.7 × 10−10 |
| rs61762674 | SNTB1 | 8 | 121561028 | 503 | 0.002 | 1.5×10−3 | 0.04 | 0.01 |
| rs55761427 | A2M | 12 | 9243017 | 501 | 0.011 | 3.1×10−3 | 0.13 | 0.01 |
| rs142230440 | SPATS2 | 12 | 49884473 | 456 | 0.004 | 1.2×10−4 | 1.8 × 10−5 | 1.3 × 10−4 |
| rs1288775 | GATM | 15 | 45661678 | 501 | 0.264 | NA | 0.02 | 1.8 × 10−7 |
| rs41280102 | SCN4A | 17 | 62028920 | 456 | 0.009 | 1.3×10−3 | 0.42 | 0.01 |
| rs52797880 | APOH | 17 | 64216854 | 503 | 0.054 | NA | 4.7 × 10−5 | 4.0× 10−6 |
a
Build GRCh37
b
Estimated using N>3000 with genotypes