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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: AIDS Behav. 2016 Jan;20(0 1):197–214. doi: 10.1007/s10461-015-1145-4

Table 4.

Comparison of Scientific Yield and Costs of Three Experimental Design Alternatives

Individual experiments Complete factorial design Fractional factorial design (half fraction)
Interaction effects Cannot be estimated All can be estimated Two-way interactions can be estimated
Number of experimental conditions 10 32 16
Experimental condition costs @ $2,000/condition $20,000 $64,000 $32,000
Number of subjects 2,525 505 505
Subject costs @ $100/subject $252,500 $50,500 $50,500
Total costs $272,500 $114,500 $82,500