Table 1.
Mean (SD) associated with time domain P3 peak amplitude (μV), and P3 latency (ms) by assessment age, and results of statistical comparisons
| P3 Amplitude & Latency by Assessment Age | ANOVA results | |||||
|---|---|---|---|---|---|---|
| Age-17 Mean (SD) |
Age-29 Mean (SD) |
Group (G) | Age (A) | G x A | ||
| p-values | ||||||
| Controls (n = 74) | Amplitude | 27.14 (7.22) | 16.05 (3.73) | ________ | ________ | ________ |
| Latency | 455.01 (57.93) | 394.26 (38.18) | ________ | ________ | ________ | |
| ADHD (n = 19) | Amplitude | 24.43 (5.18) | 12.10 (3.84) | .089 | <.001 | .413 |
| Latency | 450.21 (60.79) | 419.03 (56.05) | .455 | <.001 | .048 | |
| ODD (n = 30) | Amplitude | 22.74 (7.65) | 12.80 (3.63) | .002 | <.001 | .565 |
| Latency | 444.61 (60.23) | 398.08 (38.73) | .955 | <.001 | .279 | |
| CD (n = 62) | Amplitude | 22.25 (7.82) | 12.97 (5.02) | <.001 | <.001 | .166 |
| Latency | 446.13 (65.73) | 396.52 (42.22) | .617 | <.001 | .333 | |
| AAB (n = 45) | Amplitude | 21.36 (6.68) | 12.53 (3.96) | <.001 | <.001 | .069 |
| Latency | 442.56 (72.46) | 393.61 (40.18) | .437 | <.001 | .302 | |
| Alcohol (n = 115) | Amplitude | 23.59 (7.37) | 13.74 (3.97) | <.001 | <.001 | .205 |
| Latency | 450.07 (61.73) | 396.97 (43.24) | .937 | <.001 | .461 | |
| Nicotine (n = 113) | Amplitude | 23.33 (7.13) | 13.31 (4.40) | <.001 | <.001 | .386 |
| Latency | 454.56 (66.26) | 398.02 (44.61) | .723 | <.001 | .859 | |
| Illicit Drugs (n = 45) | Amplitude | 23.50 (7.24) | 13.34 (3.98) | <.001 | <.001 | .453 |
| Latency | 452.22 (69.06) | 396.91 (41.64) | .649 | <.001 | .599 | |
| Any-EXT (n = 185) | Amplitude | 23.57 (7.19) | 13.56 (4.29) | <.001 | <.001 | .302 |
| Latency | 454.91 (62.59) | 399.25 (43.95) | .407 | <.001 | .784 | |
Note: The reported sample sizes for the various groups reflect lifetime diagnostic status by age 29. ADHD = Attention-Deficit Hyperactivity Disorder; ODD = Oppositional Defiant Disorder; CD = Conduct Disorder; AAB = Adult Antisocial Behavior; Alcohol/Nicotine/Illicit Drugs = meeting lifetime dependence for these substances by age 29; Any-EXT = participants who met lifetime diagnosis for any of the seven EXT disorders in the study by age 29.