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SAM identifies reactivities associated with ACAAs against type I interferons and GM-CSF. Three-class SAM was applied based on cytokine reactivity to type I interferons, GM-CSF, or neither. SAM identified 14 statistically significant differences. These targets include cytokines purchased from multiple vendors. GMCSF reactivity and type I interferon–associated reactivity are boxed in green and purple, respectively, for emphasis.
