Fig 4.

Multivariate regression analysis of all forty Procrustes shape coordinates on centroid size. The plot illustrates differences in allometric variation between the euploid and trisomic mice. Both Ts;Ptch^+/− (dashed convex hull) and Ts;WT (solid convex hull) mice are considerably smaller than the euploids, and show more variation in aspects of shape than size. The euploids are distinct from the trisomic mice in shape and are larger in size, with the Eu;Ptch^+/− (dashed convex hull) being slightly larger in size than the Eu;WT (solid convex hull).