Figure 2.

Group differences in global metrics of WM structural connectome. The bar and error bar represent the mean values and standard deviations of the network properties in each group after removing the effects of age, gender and APOE ɛ4, respectively. Significantly reduced global efficiency, local efficiency, clustering coefficient and increased Lp and lambda of WM networks in risk allele carriers relative to the noncarriers were observed (all P < 0.05). [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]