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. Author manuscript; available in PMC: 2017 Feb 15.
Published in final edited form as: Int J Cancer. 2015 Oct 27;138(4):901–911. doi: 10.1002/ijc.29823

Figure 5.

Figure 5

HPV pseudoviruses infect established xenograft human ovarian tumors but not healthy tissue in vivo. Human ovarian tumors passaged only in immune-compromised animals were subcutaneously implanted. When tumors were between 7–15mm in diameter, animals received an intratumoral injection of 50µl PBS or 50µl 2×10^7 IU HPV16-Luc (a) or RFP (b) PsV. Non-tumored animals received a subcutaneous injection in their hind flank. Luminescence values are reported as average radiance (a) and micrographs (b) depict RFP expression (Red=RFP; Blue=DAPI) as a readout for PsV infection. n= 2–11/group.